{"id":1149,"date":"2017-03-16T09:00:00","date_gmt":"2017-03-16T02:00:00","guid":{"rendered":"https:\/\/www.dnacenter-thailand.com\/service\/%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%95%e0%b8%a3%e0%b8%a7%e0%b8%88%e0%b8%ab%e0%b8%b2%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b8%9c%e0%b8%b4%e0%b8%94%e0%b8%9b%e0%b8%81%e0%b8%95%e0%b8%b4%e0%b9%82%e0%b8%84\/"},"modified":"2017-03-16T09:00:00","modified_gmt":"2017-03-16T02:00:00","slug":"%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%95%e0%b8%a3%e0%b8%a7%e0%b8%88%e0%b8%ab%e0%b8%b2%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b8%9c%e0%b8%b4%e0%b8%94%e0%b8%9b%e0%b8%81%e0%b8%95%e0%b8%b4%e0%b9%82%e0%b8%84","status":"publish","type":"dna_service","link":"https:\/\/www.dnacenter-thailand.com\/en\/service\/%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%95%e0%b8%a3%e0%b8%a7%e0%b8%88%e0%b8%ab%e0%b8%b2%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b8%9c%e0%b8%b4%e0%b8%94%e0%b8%9b%e0%b8%81%e0%b8%95%e0%b8%b4%e0%b9%82%e0%b8%84\/","title":{"rendered":"Chromosome Testing in Leukemia Patients"},"content":{"rendered":"<p style=\"text-align: center;\">&nbsp;<\/p>\n<p><center style=\"box-sizing: border-box; color: rgb(85, 85, 85); font-family: &quot;Open Sans&quot;, Helvetica, Arial, sans-serif; font-size: 13px;\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/legacy\/public\/dnawire4.png\" alt=\"\" \/><\/center><\/p>\n<p>\nDetecting chromosomal abnormalities in leukemia or other blood-cancer patients. Chromosomal abnormalities are found in over 60% of leukemia patients and are a major cause of leukemia. Detecting them helps diagnose which type of disease it is; once the disease is known, it guides the treatment approach and, finally, is used to monitor whether treatment is effective or the approach needs to change. Clearly, chromosome testing in these patients is important for several reasons.<\/p>\n<p>Chromosome testing in cancer patients differs from testing in newborns and in couples. The sample used is the patient's bone marrow. The laboratory cultures the leukemia patient's bone marrow in cell-culture medium but does not stimulate the cells to divide, stimulating division would prevent us from knowing the patient's true chromosome status, as it would instead drive normal cells to divide. The chromosomes are then stained and examined for abnormalities. Because cancer-cell abnormalities are more complex than in other cases, detecting them requires extra care and greater expertise.&nbsp;<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" src=\"\/wp-content\/uploads\/legacy\/upload\/dnawire5.png\" width=\"626\" height=\"400\" align=\"left\" alt=\"\" hspace=\"30\" \/>The chromosomes are then stained and arranged to analyze for abnormalities. In the past this arrangement was done by photographing and cutting by hand; today we have computerized chromosome analyzers to assist, making the work faster and more accurate. Preparing chromosomes and analyzing abnormalities must be done by specialists in this field; sometimes small abnormalities are missed by those without enough experience, so chromosomal abnormalities go unseen and the diagnosis differs from reality. Our laboratory has examined chromosomes from leukemia patients since 1997, testing about 2,000-3,000 patients per year. Their bone marrow samples come from hospitals across the country that have no chromosome laboratory specialists.<\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>Detection of chromosomal abnormalities in leukemia and other blood-cancer patients. Chromosomal abnormalities are found in over 60% of leukemia patients.<\/p>","protected":false},"featured_media":1202,"menu_order":0,"template":"","meta":[],"dna_topic":[],"class_list":["post-1149","dna_service","type-dna_service","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/dna_service\/1149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/dna_service"}],"about":[{"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/types\/dna_service"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/media\/1202"}],"wp:attachment":[{"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/media?parent=1149"}],"wp:term":[{"taxonomy":"dna_topic","embeddable":true,"href":"https:\/\/www.dnacenter-thailand.com\/en\/wp-json\/wp\/v2\/dna_topic?post=1149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}